A UTI (Urinary Track Infection) is an infection in the urinary system caused by bacteria. It is more common in women and can affect the kidneys, ureters, bladder, and urethra.
- 50% of women experience at least 1 UTI in their lifetime
- UTIs contribute to 10.5 million doctor visits annually and $3 billion in healthcare spend in the US alone
- Untreated UTIs can lead to sepsis and kidney disorders
5 Risk Factors of Urinary Track Infection
Menopause
Urinary Track Abnormalities
Sex
Pregnancy
Diabetes
Menopause
Menopause
Drop in estrogen levels make the body susceptible to UTIsUrinary Track Abnormalities
Urinary Track Abnormalities
An abnormal shape of urinary track could block urine flow and lead to bacteria build upSex
Sex
Bacteria can enter the urinary track during sex and multiplyPregnancy
Pregnancy
Growing uterus puts pressure on the bladder and urethra, obstructing the flow of urineDiabetes
Diabetes
Diabetes causes changes in the immune system and urine flow resulting in higher risk for UTIsKnow The enemy
The Bacteria driving UTI*
Strains of these bacteria reside in the anus and vagina. When these bacteria enter the uterus or bladder it could lead to a UTI
Key note: Some other strains of bacteria such as vaginal lactobacilli are essential to prevent UTIs and maintain vaginal health
*Uncomplicated UTI
The enemy is getting smarter
Bacteria are evolving and cases of antimicrobial resistance are on the rise
In particular, multiple strains of E.coli are developing resistance to current antibiotic treatments
Alternate approaches in treating UTIs are the need of the hour
2050 projection: Yearly Deaths from antimicrobial infections and other causes
10
M
Antimicrobial resistance (AMR)
8
M
Cancer
1.5
M
Diabetes
Source: Review on Antimicrobial Resistance
3 Treatment options for UTI
Antibiotics
Antibiotics are the go to standard of care for UTIs . Trimethoprim-sulfamethoxazole is used as the first line treatment by many GPs
Targeted Supplements
Emerging class of organic products and probiotics that prevent or reduce UTI symptoms. D-Mannose, Cranberry extract are strong candidates
Estrogen Therapy
For women in menopause, vaginal estrogen therapy can help boost immunity and improve vaginal microbiome health
Her-bio approach
Targeted ingredients with robust long term safety profiles , to not only treat but prevent UTIs
Target Health Goals
- Prevent UTIs
- Alleviate UTI inflammation
- Boost Immunity